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Primary versus acquired epidermal growth factor receptor Thr790Met mutant non-small cell lung cancer: clinical features and prognoses.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Jun 2024

Zhou Siqi, Cai Guoxin, Meng Xue, Li Mengying, Fu Ying, Wang Xiaohan, Wang Kaiyue, Han Xiao

Abstract excerpt

PURPOSE: This study aimed to identify the impact of epidermal growth factor receptor (EGFR) T790M mutations on clinical characteristics and prognosis. METHODS: Retrospective analyses were conducted on the differences on clinicopathological features and prognosis between primary and acquired T790M mutations. Subgroup analyses were performed for primary T790M coexisting with other mutations. RESULTS: Patients with...

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PMID: 38190033
DOI: 10.1007/s12094-023-03365-5

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