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Article

Identification of eight genomic protective alleles for mitochondrial diabetes by Kinship-graph convolutional network.

Journal of diabetes investigation - 1 Jan 2024

Wang Jiahao, Yan Dandan, Cui Haoyue, Zhang Rong, Ma Xiaojing, Chen Luonan, Hu Cheng, Wu Jiarui

Abstract excerpt

AIMS: Nearly 85% of maternally inherited diabetes and deafness (MIDD) are caused by the m.3243A>G mutation in the mitochondrial DNA. However, the clinical phenotypes of MIDD may also be influenced by the nuclear genome, this study aimed to investigate nuclear genome variants that influence clinical phenotypes associated with m.3243A>G mutation in MIDD based on whole-genome sequencing of the patients belonging to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38157301
DOI: 10.1111/jdi.14125
PMCID: PMC10759726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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