Article
Molecular characterization of large cell calcifying sertoli cell tumors: A multi-institutional study of 6 benign and 2 malignant tumors.
Human pathology - 1 Feb 2024
Abdulfatah Eman, Al-Obaidy Khaleel I, Robinson Dan, Wu Yi-Mi, Heider Amer, Idrees Muhammad T, Ulbright Thomas M, Kunju Lakshmi Pryia, Wu Angela
Abstract excerpt
Large cell calcifying Sertoli cell tumors (LCCSCTs) are rare testicular tumors, representing <1 % of all testicular neoplasms. Almost 40 % of patients with LCCSCTs will present in the context of the inherited tumor predisposition syndrome, the Carney complex. While most LCCSCTs are benign, 10-20 % have malignant behavior. The aim of our study was to analyze LCCSCTs for novel molecular alterations in addition to...
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