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Article

Insight into the mechanism of gallstone disease by proteomic and metaproteomic characterization of human bile

4 Dec 2023

Abstract excerpt

Introduction: Cholesterol gallstone disease is a prevalent condition that has a significant economic impact. However, the role of the bile microbiome in its development and the host's responses to it remain poorly understood. Methods: In this study, we conducted a comprehensive analysis of microbial and human bile proteins in 40 individuals with either gallstone disease or gallbladder polyps. We employed a...

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PMID: 38111640
DOI: 10.3389/fmicb.2023.1276951

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