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Article

Liquid biopsy in clinical outcomes and detection of T790M mutation in metastatic non-small cell lung cancer after progression to EGFR-TKI.

Cancer biomarkers : section A of Disease markers - 1 Jan 2025

Heredia David, Bolaño-Guerra Laura, Valencia-Velarde Angel, Santoyo Edgar Varela, Lara-Mejía Luis, Cárdenas-Fernández Daniela, Orozco Mario, Cruz-Rico Graciela, Arrieta Oscar

Abstract excerpt

BACKGROUNDLiquid biopsy (LB) is used to detect epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) and has been demonstrated to have prognostic and predictive value.OBJECTIVETo associate the rates of EGFR and T790M mutations detected by LB during disease progression after first- or second-generation EGFR-TKIs with clinical characteristics and survival outcomes.METHODSFrom...

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Identifiers

PMID: 38108344
DOI: 10.3233/CBM-230124
PMCID: PMC12288383

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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