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Article

Autoinflammatory keratinization diseases: An emerging concept encompassing various inflammatory keratinization disorders of the skin.

Journal of dermatological science - 1 May 2018

Akiyama Masashi, Takeichi Takuya, McGrath John A, Sugiura Kazumitsu

Abstract excerpt

Classifying inflammatory skin diseases is challenging, especially for the expanding group of disorders triggered by genetic factors resulting in hyperactivated innate immunity that result in overlapping patterns of dermal and epidermal inflammation with hyperkeratosis. For such conditions, the umbrella term "autoinflammatory keratinization diseases" (AIKD) has been proposed. AIKD encompasses diseases with mixed...

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Source

Identifiers

PMID: 29422292
DOI: 10.1016/j.jdermsci.2018.01.012

Genes

CARD14
NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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