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Generation of a bank of clinical-grade, HLA-homozygous iPSC lines with high coverage of the Spanish population

13 Dec 2023

Abstract excerpt

BACKGROUND: Induced pluripotent stem cell (iPSC)-derived cell therapies are an interesting new area in the field of regenerative medicine. One of the approaches to decrease the costs of iPSC-derived therapies is the use of allogenic homozygous human leukocyte antigen (HLA)-matched donors to generate iPSC lines and to build a clinical-grade iPSC bank covering a high percentage of the Spanish population. METHODS:...

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PMID: 38093328
DOI: 10.1186/s13287-023-03576-1

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