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Article

Remodeling of the gastric environment in Helicobacter pylori -induced atrophic gastritis

7 Dec 2023

Abstract excerpt

ABSTRACT Helicobacter pylori colonization of the human stomach is a strong risk factor for gastric cancer. To investigate H. pylori -induced gastric molecular alterations, we used a Mongolian gerbil model of gastric carcinogenesis. Histologic evaluation revealed varying levels of atrophic gastritis (a premalignant condition characterized by parietal and chief cell loss) in H. pylori -infected animals, and...

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Identifiers

PMID: 38059647
DOI: 10.1128/msystems.01098-23

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