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Article

Association of white matter hyperintensities with long-term EGFR-TKI treatment and prediction of progression risk.

Brain and behavior - 1 Dec 2023

Yang Hang, Meng Rui, Jiang Junjie, Luo Yan, Deng Xiaolin, Yang Sibo, Chen Shengcai, Wu Jiehong, Wan Yan, Li Yanan, Jin Huijuan, He Quanwei, Wang David, Chang Jiang, Yang Kunyu, Zhou Yifan, Hu Bo

Abstract excerpt

PURPOSE: The purpose of this study was to test the hypothesis that brain white matter hyperintensities (WMH) are more common in patients receiving epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) and identify clinical risk factors associated with WMH. EXPERIMENTAL DESIGN: This multiple-center, prospective cohort study was conducted from March 2017 to July 2020. Two groups of patients with...

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Identifiers

PMID: 38054663
DOI: 10.1002/brb3.3326
PMCID: PMC10726800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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