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Combined Furmonertinib and Intrathecal Chemotherapy for Leptomeningeal Metastasis from Non-Small Cell Lung Cancer: Efficacy, Safety, and CSF Drug Concentrations

2026-08-07

Abstract excerpt

<title>Abstract</title> <p> Purpose This study evaluates the efficacy and safety of furmonertinib combined with intrathecal chemotherapy at different doses in patients with leptomeningeal metastasis(LM) from non-small cell lung cancer(NSCLC). We analyze factors influencing treatment efficacy and measure furmonertinib concentrations in the cerebrospinal fluid, thereby providing a reference for precision pharmaco...

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Literature Corpus work
92b3bafe-1e6a-50b6-986e-e9d7d4bf7104
DOI
10.21203/rs.3.rs-10549528/v1
Open publication

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Combined Furmonertinib and Intrathecal Chemotherapy for Leptomeningeal Metastasis from Non-Small Cell Lung Cancer: Efficacy, Safety, and CSF Drug ConcentrationsDOI 10.21203/rs.3.rs-10549528/v1
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