Article
11 C-Acetate PET/CT for Reactive Astrogliosis Outperforms 11 C-Methionine PET/CT in Glioma Classification and Survival Prediction.
Clinical nuclear medicine - 1 Feb 2024
Kim Dongwoo, Yi Ju Hyeon, Park Youngjoo, Kim Sun Jung, Kang Seok-Gu, Kim Se Hoon, Chun Joong-Hyun, Chang Jong Hee, Yun Mijin
Abstract excerpt
PURPOSE: 11 C-acetate (ACE) PET/CT visualizes reactive astrogliosis in tumor microenvironment. This study compared 11 C-ACE and 11 C-methionine (MET) PET/CT for glioma classification and predicting patient survival. PATIENTS AND METHODS: In this prospective study, a total of 142 patients with cerebral gliomas underwent preoperative MRI, 11 C-MET PET/CT, and 11 C-ACE PET/CT. Tumor-to-contralateral cortex (TNR MET...
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