Article
11 C-Acetate PET/CT Detects Reactive Astrogliosis Helping Glioma Classification.
Clinical nuclear medicine - 1 Oct 2022
Kim Dongwoo, Chun Joong Hyun, Yi Ju Hyeon, Ko Hae Young, Chung Jee-In, Lee Misu, Park Yongmin Mason, Nam Min-Ho, Kim Jisu, Kim Seon Yoo, Park Youngjoo, Moon Ju Hyung, Kang Seok-Gu, Chang Jong Hee, Lee C Justin, Kim Se Hoon, Yun Mijin
Abstract excerpt
PURPOSE: 11 C-acetate ( 11 C-ACE) uptake on PET/CT was recently discovered to represent reactive astrocytes in the tumor microenvironment. This study aimed at evaluating the role of 11 C-ACE PET/CT as an imaging biomarker of reactive astrogliosis in characterizing different types of gliomas. METHODS: In this prospective study, a total of 182 patients underwent 11 C-ACE PET/CT before surgery. The ratio of SUV max...
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