Article
Classifying Alzheimer's disease and normal subjects using machine learning techniques and genetic-environmental features.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Jun 2024
Huang Yu-Hua, Chen Yi-Chun, Ho Wei-Min, Lee Ren-Guey, Chung Ren-Hua, Liu Yu-Li, Chang Pi-Yueh, Chang Shih-Cheng, Wang Chaung-Wei, Chung Wen-Hung, Tsai Shih-Jen, Kuo Po-Hsiu, Lee Yun-Shien, Hsiao Chun-Chieh
Abstract excerpt
BACKGROUND: Alzheimer's disease (AD) is complicated by multiple environmental and polygenetic factors. The accuracy of artificial neural networks (ANNs) incorporating the common factors for identifying AD has not been evaluated. METHODS: A total of 184 probable AD patients and 3773 healthy individuals aged 65 and over were enrolled. AD-related genes (51 SNPs) and 8 environmental factors were selected as features...
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