Article
Integrating compositional and functional content to describe vaginal microbiomes in health and disease
29 Nov 2023
Abstract excerpt
BACKGROUND: A Lactobacillus-dominated vaginal microbiome provides the first line of defense against adverse genital tract health outcomes. However, there is limited understanding of the mechanisms by which the vaginal microbiome modulates protection, as prior work mostly described its composition through morphologic assessment and marker gene sequencing methods that do not capture functional information. To...
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