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Article

Investigation of the effects of oxidative stress, inflammation on the pathway of tryptophan/kynurenine in OCD.

Acta neuropsychiatrica - 28 Nov 2023

Delen Elif, Kucukali Cem Ismail, Karaaslan Zerrin, Yuceer Hande, Punar Seyma, Hakan Mehmet Tolgahan, Yaylim Ilhan, Ozkok Elif

Abstract excerpt

OBJECTIVES: Recent studies have shown that the distribution of the tryptophan/kynurenine pathway (KP) plays a role in the development of obsessive-compulsive disorder (OCD). We aimed to reveal the relationship between CYP1A1 rs464903 and aryl hydrocarbon receptor (AhR) rs10249788 associated with the KP and interferon gamma (IFN γ) and oxidative stress in OCD. METHODS: In our study, the serum and DNAs of 150...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Basic Helix-Loop-Helix Proteins
Share to Cytochrome P-450 CYP1A1
Share to Glutathione Peroxidase
Share to Kynurenine
Share to Obsessive-Compulsive Disorder
Share to Receptors, Aryl Hydrocarbon
Share to Thiobarbituric Acid Reactive Substances
Share to Tryptophan

Source

Open in PubMed Open full text

Identifiers

PMID: 38012854
DOI: 10.1017/neu.2023.55
PMCID: PMC13130382

Genes

CYP1A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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