Article
Anhedonia in adolescents at transdiagnostic familial risk for severe mental illness: Clustering by symptoms and mechanisms of association with behavior.
Journal of affective disorders - 15 Feb 2024
Gupta T, Eckstrand K L, Lenniger C J, Haas G L, Silk J S, Ryan N D, Phillips M L, Flores L E, Pizzagalli D A, Forbes E E
Abstract excerpt
BACKGROUND: Anhedonia is a transdiagnostic symptom of severe mental illness (SMI) and emerges during adolescence. Possible subphenotypes and neural mechanisms of anhedonia in adolescents at risk for SMI are understudied. METHODS: Adolescents at familial risk for SMI (N = 81) completed anhedonia (e.g., consummatory, anticipatory, social), demographic, and clinical measures and one year prior, a subsample (N = 46)...
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