The effects of 17α‐methyltestosterone on gonadal histology and gene expression along hypothalamic‐pituitary‐gonadal axis, germ cells, sex determination, and hypothalamus‐pituitary‐thyroid axis in zebrafish ( Danio rerio )

Abstract excerpt

As a synthetic androgen, 17α-methyltestosterone (MT) is widely used in aquaculture to induce sex reversal and may pose a potential risk to aquatic organisms. This ecological risk has attracted the attention of many scholars, but it is not comprehensive enough. Thus, the adverse effects of MT on zebrafish (Danio rerio) were comprehensively evaluated from gonadal histology, as well as the mRNA expression levels of...

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