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Article

Novel ACTL7A variants in males lead to fertilization failure and male infertility.

Andrology - 1 Jul 2025

Wang Meng, Zhou Juepu, Long Rui, Jin Huizi, Gao Limin, Zhu Lixia, Jin Lei

Abstract excerpt

BACKGROUND: Total fertilization failure occurs in 1%-3% of all intracytoplasmic sperm injection cycles. Genetic defects are found to be crucial causes responsible for total fertilization failure after intracytoplasmic sperm injection. However, the reported genes only elucidate a small proportion of total fertilization failure cases, and more genetic defects are required to be explored. OBJECTIVE: To investigate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 37991128
DOI: 10.1111/andr.13553
PMCID: PMC12183009

Genes

ACTL7A

Variants

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

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