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Evidence based on Mendelian randomization: Causal relationship between mitochondrial biological function and lung cancer and its subtypes.

Neoplasia (New York, N.Y.) - 1 Dec 2023

Zhu Kangle, Shi Jingwei, Yang Rusong, Zhou Chu, Liu Zhengcheng

Abstract excerpt

OBJECTIVE: This study aimed to investigate the causal relationship between mitochondrial biological function and lung cancer, including its subtypes, via MR. METHODS: SNPs significantly associated with lung cancer and its subtypes were employed as instrumental variables. MR-Egger regression, simple mode, weighted mode, simple median, and weighted median, were utilized to determine the causal relationship between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37976568
DOI: 10.1016/j.neo.2023.100950
PMCID: PMC10685044

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