Article
Effects of cohort, genotype, variant, and maternal β-blocker treatment on foetal heart rate predictors of inherited long QT syndrome.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 2 Nov 2023
Kaizer Alexander M, Winbo Annika, Clur Sally-Ann B, Etheridge Susan P, Ackerman Michael J, Horigome Hitoshi, Herberg Ulrike, Dagradi Federica, Spazzolini Carla, Killen Stacy A S, Wacker-Gussmann Annette, Wilde Arthur A M, Sinkovskaya Elena, Abuhamad Alfred, Torchio Margherita, Ng Chai-Ann, Rydberg Annika, Schwartz Peter J, Cuneo Bettina F
Abstract excerpt
AIMS: In long QT syndrome (LQTS), primary prevention improves outcome; thus, early identification is key. The most common LQTS phenotype is a foetal heart rate (FHR) < 3rd percentile for gestational age (GA) but the effects of cohort, genotype, variant, and maternal β-blocker therapy on FHR are unknown. We assessed the influence of these factors on FHR in pregnancies with familial LQTS and developed a FHR/GA...
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