Effectiveness of beta-blockers depending on the genotype of congenital long-QT syndrome: A meta-analysis.

Abstract excerpt

BACKGROUND: Beta-blockers are first-line therapy in patients with congenital long-QT syndrome (LQTS). OBJECTIVE: This study sought to determine the differences in effectiveness of beta-blockers on risk reduction according to LQTS genotype. METHODS: We searched MEDLINE, EMBASE, and CENTRAL databases to investigate the use of beta-blockers (atenolol, nadolol, propranolol, and metoprolol) in patients with LQTS....

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