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Article

Development and external validation of MRI-based RAS mutation status prediction model for liver metastases of colorectal cancer.

Journal of surgical oncology - 1 Mar 2024

Han Zhe, Tong Yahan, Zhu Xiu, Sun Diandian, Jia Ningyang, Feng Yayuan, Yan Kai, Wei Yongpeng, He Jie, Ju HaiXing

Abstract excerpt

BACKGROUND: The mutation status of rat sarcoma viral oncogene homolog (RAS) has prognostic significance and serves as a key predictive biomarker for the effectiveness of antiepidermal growth factor receptor (EGFR) therapy. However, there remains a lack of effective models for predicting RAS mutation status in colorectal liver metastases (CRLMs). This study aimed to construct and validate a diagnostic model for...

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PMID: 37974474
DOI: 10.1002/jso.27508

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