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Article

MiR-20b-5p involves in vascular aging induced by hyperhomocysteinemia

16 Nov 2023

Abstract excerpt

Hyperhomocysteinemia (HHcy) is an independent risk factor of atherosclerosis (AS). Some reports have shown that homocysteine (Hcy) could accelerate the development of AS by promoting endothelial cell senescence. miRNAs were widely involved in the pathophysiology of HHcy. However, few studies have focused on the changes of miRNA-mRNA networks in the artery of HHcy patients. For this reason, RNA-sequencing was...

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PMID: 37967592
DOI: 10.1016/j.exger.2023.112330

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