Article
Immunogenicity and protective efficacy of a recombinant adenovirus containing the fusion protein of bovine parainfluenza virus type 3 genotype C in mice.
Microbial pathogenesis - 1 Dec 2023
Zhang Jiaqi, Zeng Jiangyong, Yuan Zhenjie, Huang Xiangyue, Wu Jinbo, Yu Qisheng, Chen Taoyun, Den Gunan, Zhu Chenxi, Zhang Bin
Abstract excerpt
Bovine parainfluenza virus type 3 (BPIV3) is a viral respiratory pathogen of cattle that causes substantial economic losses. A replicating-defective recombinant human adenovirus type 5 (HAd5), carrying a fusion protein of BPIV3 genotype C (HAd5-F), was constructed and evaluated for its immunogenicity and protective efficacy in mice. After intramuscular injection with the HAd5-F, the IgG titers against F proteins...
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