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Single Nucleotide Polymorphisms of the MEFV Gene E148Q Are Highly Associated With Disease Phenotype in Crohn's Disease.

Inflammatory bowel diseases - 3 Jun 2024

Yamada Satoshi, Honzawa Yusuke, Yamamoto Shuji, Matsuura Minoru, Kitamoto Hiroki, Okabe Makoto, Kakiuchi Nobuyuki, Toyonaga Takahiko, Kobayashi Taku, Hibi Toshifumi, Seno Hiroshi, Nakase Hiroshi

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) of the MEFV gene may modify inflammatory bowel disease (IBD) activity. The prevalence of MEFV gene SNPs in IBD patients and their involvement in IBD pathophysiology remains unclear. METHODS: We analyzed 12 MEFV gene SNPs in peripheral leukocytes of Japanese IBD patients (Crohn's disease [CD]: 69 patients, ulcerative colitis: 32 patients) by polymerase chain...

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PMID: 37951297
DOI: 10.1093/ibd/izad259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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