Encystation stimuli sensing is mediated by adenylate cyclase AC2-dependent cAMP signaling in Giardia

Abstract excerpt

Protozoan parasites use cAMP signaling to precisely regulate the place and time of developmental differentiation, yet it is unclear how this signaling is initiated. Encystation of the intestinal parasite Giardia lamblia can be activated by multiple stimuli, which we hypothesize result in a common physiological change. We demonstrate that bile alters plasma membrane fluidity by reducing cholesterol-rich lipid...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Parasitic Infections and Diagnostics
• Share to Pneumocystis jirovecii pneumonia detection and treatment
• Share to Toxoplasma gondii Research Studies