Article
[The role of endothelin-1 in the pathogenesis of familial exudative vitreoretinopathy].
Vestnik oftalmologii - 1 Jan 2023
Katargina L A, Chesnokova N B, Denisova E V, Geraskina E A, Pavlenko T A, Beznos O V, Lisovskaja O A
Abstract excerpt
Familial exudative vitreoretinopathy (FEVR) is a rare hereditary disease characterized by pathological retinal vascularization with a progressive and variable course. The mechanisms of disease progression remain unclear. One substance that plays an important role in the pathogenesis of retinal vascular diseases is endothelin (ET). It was found that tissue hypoxia enhances the expression of the gene encoding ET-1,...
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