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Gut microbiota composition and diversity before, during, and two months after rifamycin-based tuberculosis preventive therapy

2 Nov 2023

Abstract excerpt

Tuberculosis (TB) preventive therapy (TPT) is an effective strategy to eliminate TB in low-incidence settings. Shorter TPT regimens incorporating the antimicrobial class of rifamycins are designed to improve adherence and completion rates but carry the risk of modifications to the gut microbiota. We enrolled six subjects diagnosed with latent TB infection (LTBI) who accepted to initiate TPT. We also enrolled six...

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PMID: 37919333
DOI: 10.1038/s41598-023-44854-5

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