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Article

Elevated high-mannose N-glycans hamper endometrial decidualization

14 Oct 2023

Abstract excerpt

Decidualization of endometrial stromal cells is a hallmark of endometrial receptivity for embryo implantation, and dysfunctional decidualization is associated with pregnancy failure. Protein glycosylation is an important posttranslational modification that affects the structure and function of glycoproteins. Our results showed that high-mannose epitopes were elevated in the decidual tissues of miscarriage...

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PMID: 37915610
DOI: 10.1016/j.isci.2023.108170

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