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An early clinical phenotype of necrotizing meningoencephalitis in the Pug reveals similarities to multiple sclerosis in humans.

American journal of veterinary research - 1 Jan 2024

Windsor Rebecca, Stewart Samuel, Huentelman Matt, Keller Stefan, Khanna Chand

Abstract excerpt

Necrotizing meningoencephalitis (NME) is a fatal neuroinflammatory disease that previously carried a uniformly grave prognosis. Our recent identification of a novel early form of NME in Pugs suggests that disease onset and progression are likely more insidious than previously recognized and provides new hope that early therapeutic intervention may halt disease progression and ultimately prevent or cure NME. This...

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PMID: 37913632
DOI: 10.2460/ajvr.23.07.0164

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