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Article

[Association between HLA-DRB1 gene polymorphisms and genetic susceptibility of early-onset severe preeclampsia].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 15 Oct 2023

Lai Chun-Chi, Zhang Lu-Lu, Sun Meng-Ya, Sun Jun-Fang, Jiang Hong

Abstract excerpt

OBJECTIVES: To explore the correlation between the single nucleotide polymorphisms (SNP) of rs3135388, rs114293611 and rs142804168 of HLA-DRB1 gene and early-onset severe preeclampsia (sPE). METHODS: Blood samples were collected from 102 early-onset sPE mothers and their neonates (sPE group), as well as 120 normotensive mothers and their neonates (control group). Sanger sequencing was performed to compare the...

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Share to Alleles
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Share to Genetic Predisposition to Disease
Share to HLA-DRB1 Chains
Share to Infant, Newborn
Share to Polymorphism, Single Nucleotide
Share to Pre-Eclampsia
Share to Pregnancy

Source

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Identifiers

PMID: 37905758
DOI: 10.7499/j.issn.1008-8830.2303100
PMCID: PMC10621060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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