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Article

Loss of CDH16 expression is a strong independent predictor for lymph node metastasis in Middle Eastern papillary thyroid cancer.

Scientific reports - 29 Oct 2023

Siraj Abdul K, Parvathareddy Sandeep Kumar, Al-Rasheed Maha, Annaiyappanaidu Padmanaban, Siraj Nabil, Lennartz Maximilian, Al-Sobhi Saif S, Al-Dayel Fouad, Sauter Guido, Al-Kuraya Khawla S

Abstract excerpt

Papillary Thyroid Cancer (PTC) is the most common type of thyroid cancer. The membrane-associated glycoprotein cadherin-16 (CDH16) plays a significant role in the embryonal development of thyroid follicles and cell adhesion. Previous studies have indicated a substantial downregulation of CDH16 in PTC. However, its role in Middle Eastern PTC has not been elucidated. We analyzed a tissue microarray comprising 1606...

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Identifiers

PMID: 37899424
DOI: 10.1038/s41598-023-45882-x
PMCID: PMC10613612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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