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Article

Aberrant Expression of Thymosin Beta-4 Correlates With Advanced Disease and BRAF V600E Mutation in Thyroid Cancer.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Oct 2022

Kuo Chi-Yu, Jhuang Jie-Yang, Huang Wen-Chien, Cheng Shih-Ping

Abstract excerpt

Thymosin beta-4 (TMSB4X) was recently identified as a differentially expressed gene between malignant and non-malignant thyroid cells via single-cell RNA sequencing. In the present study, we aimed to study the immunostaining pattern of TMSB4X in benign and malignant thyroid neoplasms. Immunohistochemical analysis revealed that normal thyroid tissue or benign thyroid disorders exhibited undetectable...

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Identifiers

PMID: 36321670
DOI: 10.1369/00221554221138370
PMCID: PMC9660367

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