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Article

Class I HLA Allele Predicted Restricted Antigenic Coverages for Fap2 Protein of Fusobacterium Nucleatum Are Associated with Colorectal Cancer Incidence.

Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2023

Zeddou Mustapha

Abstract excerpt

OBJECTIVE: This study investigates the association between HLA-A and -B allele diversity, Fusobacterium nucleatum Fap2 protein-derived antigenic coverage, and colorectal cancer (CRC) epidemiology across diverse populations. METHODS: We examined 75 HLA-I alleles and explored 698 potential HLA-A and B-restricted Fap2-derived antigens, assessing how 21 countries may respond to these peptides based on their HLA-I...

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Identifiers

PMID: 37898872
DOI: 10.31557/APJCP.2023.24.10.3629
PMCID: PMC10770689

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