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Gonococcal OMV-delivered PorB induces epithelial cell mitophagy

23 Feb 2024

Abstract excerpt

The bacterial pathogen Neisseria gonorrhoeae is able to invade epithelial cells and survive intracellularly. During this process, it secretes outer membrane vesicles (OMVs), however, the mechanistic details for interactions between gonococcal OMVs and epithelial cells and their impact on intracellular survival are currently not established. Here, we show that gonococcal OMVs induce epithelial cell mitophagy to...

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PMID: 38396029
DOI: 10.1038/s41467-024-45961-1

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