Article
Molecular Markers Are Associated with Onset of Radioiodine Refractoriness in Patients with Papillary Thyroid Carcinoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Dec 2023
Laschinsky Christina, Theurer Sarah, Herold Thomas, Rawitzer Josefine, Weber Frank, Herrmann Ken, Brandenburg Tim, Führer-Sakel Dagmar, Fendler Wolfgang P, Weber Manuel
Abstract excerpt
The onset of radioiodine-refractory thyroid carcinoma (RR-TC) is a negative predictor of survival and has been linked to the presence of BRAFV600E mutations in papillary thyroid cancer. We aimed to identify further genetic alterations associated with RR-TC. Methods: We included 38 patients with papillary thyroid cancer who underwent radioiodine imaging and 18F-FDG PET/CT after total thyroidectomy. The molecular...
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