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Article

Integrin αvβ1 facilitates ACE2-mediated entry of SARS-CoV-2

2 Nov 2023

Abstract excerpt

Integrins have been suggested to be involved in SARS-CoV-2 infection, but the underlying mechanisms remain largely unclear. This study aimed to investigate how integrins facilitate the ACE2-mediated cellular entry of SARS-CoV-2. We first tested the susceptibility of a panel of human cell lines to SARS-CoV-2 infection using the spike protein pseudotyped virus assay and examined the expression levels of integrins...

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PMID: 37884208
DOI: 10.1016/j.virusres.2023.199251

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