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Article

Lymphocyte integrins mediate entry and dysregulation of T cells by SARS-CoV-2

27 Feb 2023

Abstract excerpt

T-cell infection by SARS-CoV-2 and associated immune responses are correlated with disease severity and prognosis of COVID-19. Lymphopenia is associated with increased disease severity in COVID-19. Significantly lower circulating T and B cell counts were observed in patients who died from COVID-19 compared with survivors. Moreover, SARS-CoV-2 infection causes aberrant lymphocyte activation and dysfunction....

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PMID: 36849525
DOI: 10.1038/s41392-023-01348-0

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