Article
Epilepsy in gliomas: recent insights into risk factors and molecular pathways.
Current opinion in neurology - 1 Dec 2023
Rudà Roberta, Bruno Francesco, Pellerino Alessia
Abstract excerpt
PURPOSE OF REVIEW: The purpose of this review is to discuss the molecular pathways governing the development of seizures in glioma patients. RECENT FINDINGS: The intrinsic epileptogenicity of the neuronal component of glioneuronal and neuronal tumors is the most relevant factor for seizure development. The two major molecular alterations behind epileptogenicity are the rat sarcoma virus (RAS)/mitogen-activated...
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