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Proteomics identifies apoptotic markers as predictors of histological transformation in patients with follicular lymphoma

12 Oct 2023

Abstract excerpt

Follicular lymphoma (FL) is an indolent lymphoma with a generally favorable prognosis. However, histological transformation (HT) to a more aggressive disease leads to markedly inferior outcomes. This study aims to identify biological differences predictive of HT at the time of initial FL diagnosis. We show differential protein expression between diagnostic lymphoma samples from patients with subsequent HT...

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PMID: 37824846
DOI: 10.1182/bloodadvances.2023011299

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