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Article

Causal association between inflammatory bowel disease and 32 site-specific extracolonic cancers: a Mendelian randomization study

10 Oct 2023

Abstract excerpt

BACKGROUND: The risk of extracolonic cancer is increased in inflammatory bowel disease (IBD) patients, but it is not clear whether there is a causal relationship. We aimed to systematically estimate the causal relationship between IBD and extracolonic cancers. METHODS: Independent genetic variants strongly associated with IBD were extracted as instrumental variables from genome-wide association study (GWAS)...

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PMID: 37817217
DOI: 10.1186/s12916-023-03096-y

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