Article
Concordance study on Y-STRs typing between SeqStudio™ genetic analyzer for HID and MiSeq™ FGx forensic genomics system.
Molecular biology reports - 1 Dec 2023
Soldati Giulia, Turrina Stefania, Treccani Mirko, Saccardo Chiara, Ausania Francesco, De Leo Domenico
Abstract excerpt
BACKGROUND: Massively Parallel Sequencing (MPS) allowed an increased number of information to be retrieved from short tandem repeat (STR) analysis, expanding them not only to the size, as already performed in Capillary Electrophoresis (CE), but also to the sequence. MPS requires constant development and validation of the analytical parameters to ensure that the genotyping results of STRs correspond to those...
Topics
- Male
- Humans
- DNA Fingerprinting
- Microsatellite Repeats
- Genotype
- Genomics
- Sequence Analysis, DNA
- High-Throughput Nucleotide Sequencing
- DNA
- Polymorphism, Single Nucleotide