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Wolbachia interferes with Zika virus replication by hijacking cholesterol metabolism in mosquito cells

9 Oct 2023

Abstract excerpt

ABSTRACT Zika virus is a member of the arbovirus Flaviviridae family transmitted by Aedes mosquitos and it is associated with microcephaly in infants born to infected mothers. Wolbachia is an intracellular gram-negative alpha-proteobacteria that infects many species of arthropods, including mosquitos. The presence of Wolbachia in mosquitos has been shown to control the vector population and suppress arbovirus...

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PMID: 37811984
DOI: 10.1128/spectrum.02180-23

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