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A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein.

Emerging microbes & infections - 1 Dec 2023

Rathakrishnan Anusyah, Reis Ana L, Petrovan Vlad, Goatley Lynnette C, Moffat Katy, Lui Yuan, Vuong Mai T, Ikemizu Shinji, Davis Simon J, Dixon Linda K

Abstract excerpt

African swine fever virus is a complex DNA virus that causes high fatality in pigs and wild boar and has a great socio-economic impact. An attenuated genotype II strain was constructed by replacing the gene for wildtype CD2v protein with versions in which single or double amino acid substitutions were introduced to reduce or abrogate the binding to red blood cells and reduce virus persistence in blood. The mutant...

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Identifiers

PMID: 37781934
DOI: 10.1080/22221751.2023.2265661
PMCID: PMC10588529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein.PMID 37781934Read ↗

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