Article
Intraindividual variation in histone acetylation and its impact on autoimmune thyroid diseases.
Endocrine journal - 28 Dec 2023
Haga Emi, Inoue Naoya, Iwatani Yoshinori, Arakawa Yuya, Morita Emi, Hashimoto Hidemi, Noguchi Yusuke, Hidaka Yoh, Watanabe Mikio
Abstract excerpt
Autoimmune thyroid diseases (AITDs), such as Graves' disease (GD) and Hashimoto's disease (HD), are organ-specific autoimmune diseases. Histone acetylation, especially that of histone H3, is an epigenetic mechanism that regulates gene expression and is associated with the development of autoimmune diseases. However, physiological variations in histone acetylation are not yet clear, and we believe that...
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