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p53 contributes to cardiovascular diseases via mitochondria dysfunction: A new paradigm

28 Sept 2023

Abstract excerpt

Cardiovascular diseases (CVDs) are leading causes of global mortality; however, their underlying mechanisms remain unclear. The tumor suppressor factor p53 has been extensively studied for its role in cancer and is also known to play an important role in regulating CVDs. Abnormal p53 expression levels and modifications contribute to the occurrence and development of CVDs. Additionally, mounting evidence...

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PMID: 37776918
DOI: 10.1016/j.freeradbiomed.2023.09.036

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