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Mitochondrial DNA Is a Vital Driving Force in Ischemia‐Reperfusion Injury in Cardiovascular Diseases

1 Jan 2022

Abstract excerpt

According to the latest Global Burden of Disease Study, cardiovascular disease (CVD) is the leading cause of death, and ischemic heart disease and stroke are the cause of death in approximately half of CVD patients. In CVD, mitochondrial dysfunction following ischemia-reperfusion (I/R) injury results in heart failure. The proper functioning of oxidative phosphorylation (OXPHOS) and the mitochondrial life cycle in...

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PMID: 35620580
DOI: 10.1155/2022/6235747

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