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Article

Hourglass, a rapid analysis framework for heterogeneous bioimaging data, identifies sex disparity in IL-6/STAT3-associated immune phenotypes in pancreatic cancer.

The Journal of pathology - 1 Dec 2023

Aliar Kazeera, Waterhouse Henry R, Vyas Foram, Krebs Niklas, Zhang Bowen, Poulton Emily, Chan Nathan, Gonzalez Ricardo, Jang Gun Ho, Bronsert Peter, Fischer Sandra E, Gallinger Steven, Grünwald Barbara T, Khokha Rama

Abstract excerpt

Integration and mining of bioimaging data remains a challenge and lags behind the rapidly expanding digital pathology field. We introduce Hourglass, an open-access analytical framework that streamlines biology-driven visualization, interrogation, and statistical assessment of multiparametric datasets. Cognizant of tissue and clinical heterogeneity, Hourglass systematically organizes observations across spatial...

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Identifiers

PMID: 37768107
DOI: 10.1002/path.6199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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