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Article

Proteomic aptamer analysis reveals serum biomarkers associated with disease mechanisms and phenotypes of systemic sclerosis.

Frontiers in immunology - 1 Jan 2023

Motta Francesca, Tonutti Antonio, Isailovic Natasa, Ceribelli Angela, Costanzo Giovanni, Rodolfi Stefano, Selmi Carlo, De Santis Maria

Abstract excerpt

Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disease that affects multiple organs, leading to elevated morbidity and mortality with limited treatment options. The early detection of organ involvement is challenging as there is currently no serum marker available to predict the progression of SSc. The aptamer technology proteomic analysis holds the potential to correlate SSc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37753072
DOI: 10.3389/fimmu.2023.1246777
PMCID: PMC10518467

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