Article
Focused panel sequencing points to genetic predisposition in non-cirrhotic intrahepatic portal hypertension patients in India.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 1 Apr 2024
Aaron Rekha, Premkumar Kalpana, Chapla Aaron, Vijayalekshmi B, Zachariah Uday, Elias Elwyn, Kodiatte Thomas Alex, Daniel Dolly, Jude John, Balasubramanian K A, Nair Sukesh C, Thomas Nihal, Ramakrishna Banumathi, Eapen C E, Goel Ashish
Abstract excerpt
OBJECTIVE: Non-cirrhotic intrahepatic portal hypertension (NCIPH), a portal microangiopathy affecting small portal vein radicles, is a disease of Indian sub-continent. NCIPH appears to be a complex disease with interactions between inherited and acquired factors, though the exact pathophysiological mechanism is unknown. We aimed at investigating the genetic variants that might contribute to susceptibility to...
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